The differences between the sexes are the single most important fact of human society.

Gilder moved to Harvard Square the following year and became a writer modeling himself after Joan Didion. in the summer of 2000 switching the magazine's focus from politics to technology. The book publiGeorge Gilderd as the best-selling Wealth and Poverty in 1981 communicated the ideas of supply-side economics to a wide audience in the United States and the world.

In the 1990s he became an enthusiastic evangelist of technology and the Internet through several books and his newsletter the Gilder Technology Report. His 1981 bestseller Wealth and Poverty advanced a practical and moral case for capitalism during the early months of the Reagan Administration.