You just never know when somebody's gonna die. It could happen at any moment so you've got to really treat everybody that way. Just really let everybody know how you feel about them.

He has noted that there has been a change in how works on an album. On a creative spree Frusciante released six solo albums in 2004; each album explored different recording techniques and genres. Despite the common belief that most of the tracks were recorded while he was strung out on heroin in his home in the Hollywood Hills Frusciante has said that "That album was not recorded when I was a heroin addict.

Frusciante was inducted into the Rock and Roll Hall of Fame as a member of the Red Hot Chili Peppers on April 14 2012 although he did not attend the ceremony. In 2006 Stadium Arcadium Frusciante's fifth and final album with the Chili Peppers was released. Frusciante has produced and/or recorded with the Wu-Tang Clan The Mars Volta and Omar Rodriguez Lopez Swahili Blonde The Bicycle Thief Glenn Hughes Ziggy Marley Johnny Cash George Clinton and others.