Let your Medicine be something of the Nature of the Sign ascending.

Culpeper also described the medical use of foxglove the botanical precursor to digitalis used to treat heart conditions. He died of tuberculosis in London on 10 January 1654 at the age of 37. It is the most successful non-religious English text ever[citation needed] and has been in print continuously since the 17th century.

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Culpeper came from a long line of notable people including Thomas Culpeper the lover of Catherine Howard (also a distant relative) who was sentenced to death by Catherine's husband King Henry VIII. DILIGENCE I at last obtained my desire; and being warned by MR.