The element of chance in basic research is overrated. Chance is a lady who smiles only upon those few who know how to make her smile.

Selye discovered and documented that stress differs from other physical responses in that stress is stressful whether one receives good or bad news whether the impulse is positive or negative. He also pointed to an "alarm state" a "resistance state" and an "exhaustion state" largely referring to glandular states. Philadelphia: J.

He conducted much important scientific work on the hypothetical non-specific response of an organism to stressors. While he did not recognize all of the many aspects of glucocorticoids Selye was aware of their role in the stress response.