That there must be heresies is true, not onely in our Church, but also in any other; even in Doctrines hereticall there will be super-heresies, and Arians not onely divided from their Church, but also among themselves: for heads that are disposed unto Schisme...are naturally indisposed for a community, nor will ever be confined unto the order or oeconomy of one body; and therefore when they separate from others they knit but loosely among themselves; nor contented with a general breach or dichotomie with their Church, do subdivide and mince themselves almost into Atomes.

In the eighteenth century Samuel Johnson who shared Browne's love of the Latinate wrote a brief Life in which he praised Browne as a faithful Christian but gave a mixed reception to his prose:

In the nineteenth century Browne's reputation was revived by the Romantics. The German author W. The other discourse in the unique literary diptych and antithetical in style subject-matter and imagery is The Garden of Cyrus or The Quincunciall Lozenge or Network Plantations of the Ancients Artificially Naturally and Mystically Considered whose subject is the quincunx the arrangement of five units like the five-spot in dice which Browne used to demonstrate that evidence of the Platonic forms and intelligent design exist throughout Nature.

Browne's writings display a deep curiosity towards the natural world influenced by the scientific revolution of Baconian enquiry while his Christian faith exuded tolerance and goodwill towards humanity in an often intolerant era. His literary style varies according to genre resulting in a rich unusual prose that ranges from rough notebook observations to the highest baroque eloquence.