When I graduated college I needed to make money while I was pursuing acting, so I read screenplays and made a living writing coverage on them for studios.

She joined the cast of The Nine in the role of Nick's ex-wife. She also had a small role in 2006's Mission: Impossible III. Alexander and Ponti have two children Lucia Sofia (born May 12 2006) and Leonardo Fortunato (born December 20 2010).

Alexander also acted as former Secret Service/NCIS Special Agent Kate Todd for the first two seasons of NCIS. She currently stars as Chief Medical Examiner Maura Isles on the Turner Network Television series Rizzoli & Isles. She played the role of Gretchen Witter the sister of Pacey Witter on Dawson's Creek Lucy in Yes Man (2008); and Catherine in He's Just Not That Into You (2009).