I have met some highly intelligent believers, but history has no record to say that [s]he knew or understood the mind of god. Yet this is precisely the qualification which the godly must claim—so modestly and so humbly—to possess. It is time to withdraw our 'respect' from such fantastic claims, all of them aimed at the exertion of power over other humans in the real and material world.

In November 2010 Hitchens cancelled a scheduled appearance in New York where he was to debate writers David Hazony and Stephen Prothero on the subject of the Ten Commandments. He also criticised Bush's support of intelligent design and capital punishment. He will tell it really well.

His anti-religion polemic God Is Not Great sold over 500000 copies. Hitchens died on 15 December 2011 from complications arising from oesophageal cancer a disease that he acknowledged was likely due to his lifelong predilection for heavy smoking and drinking.