According to Vedanta, there are only two symptoms of enlightenment, just two indications that a transformation is taking place within you toward a higher consciousness. The first symptom is that you stop worrying. Things don't bother you anymore. You become light-hearted and full of joy. The second symptom is that you encounter more and more meaningful coincidences in your life, more and more synchronicities. And this accelerates to the point where you actually experience the miraculous. (quoted by Carol Lynn Pearson in Consider the Butterfly)

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Reviewing Susan Jacoby's book The Age of American Unreason Kaminer (2008) sees Chopra's popular reception in America as being symptomatic of many Americans' historical inability (as Jacoby puts it) "to distinguish between real scientists and those who peddled theories in the guise of science". He currently serves as an Adjunct Professor of Executive Programs at the Kellogg School of Management at Northwestern University. The documentary is directed by actress Namrata Singh Gujral and also features cancer survivors Olivia Newton-John Diahann Carroll Melissa Etheridge Mumtaz and Jaclyn Smith.

His books have been translated into 35 languages and sold more than 20 million copies worldwide. Chopra has taught at the medical schools of Tufts University Boston University and Harvard University. His critics accuse him of creating a false sense of hope in sick individuals which may keep them away from effective medical care.