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Pagano was diagnosed with acute promyelocytic leukemia in September 2012 and took an indefinite leave of absence of his coaching duties. He then underwent three months of treatment at the IU Simon Cancer Center in Indianapolis. His defensive backs did not allow a passing touchdown over the last 27 quarters of the 1999 season.
He is the brother of San Diego Chargers defensive coordinator John Pagano. Pagano has previously served as the defensive coordinator of the Baltimore Ravens in 2011. Charles D.