Our invisibility is the essence of our oppression. And until we eliminate that invisibility, people are going to be able to perpetuate the lies and myths about gay people.

O'Leary then moved to New York City and did doctoral studies in organization development at Yeshiva University. During that period Jean O'Leary became involved with the nascent gay rights movement joining the Gay Activists' Alliance (GAA) Chapter in Brooklyn and later lobbying state politicians. She co-founded National Coming Out Day with Rob Eichberg in 1987.

She had been a Roman Catholic Religious Sister before this involvement and would later write about her experience in a 1984 anthology Lesbian Nuns: Breaking Silence.