I was the center square on Hollywood Squares for about fifteen weeks.

In 1981 he worked as a disc jockey at KEZY-AM radio in Anaheim California. "In Japan the show’s called 'The Happy Boy and His Family. In 1983 Mathers reprised his role in the 1983 television reunion film Still the Beaver which also featured the majority of the original Leave It to Beaver cast.

Mathers is best known for his role in the television sitcom series Leave It to Beaver (1957–1963) in which he played Theodore "Beaver" Cleaver the younger son of archetypal suburban couple June and Ward Cleaver (played by Barbara Billingsley and Hugh Beaumont) and the brother of Wally Cleaver (played by Tony Dow).